College of Pharmacy, Al Bayan University, Iraq.
Review Article
World Journal of Biology Pharmacy and Health Sciences, 2022, 12(01), 137–147.
Article DOI: 10.30574/wjbphs.2022.12.1.0143
Received on 21 August 2022; revised on 14 October 2022; accepted on 17 October 2022
Ferritin is the main iron storage protein that plays an important role in iron homeostasis and is concerned with many physiological functions and pathologic disorders. Clinically, ferritin is mainly used as a biomarker for total body iron stores. Serum ferritin has a critical function in both iron deficiency and overload that related to the diagnosis and treatment. High levels of both serum and tissue ferritin are related to the coronary artery disorder, cancer, and bad results after stem cell transplantation. Less commonly, ferritin is related to other human diseases like the neurodegenerative complaints, sideroblastic anemias, and hemophagocytic disorder. Moreover, up to date research explains a novel function of ferritin that not related to the iron storage.
Ferritin; Iron Homeostasis; Iron storage; Ferroxidase activity
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Inaam Ahmed Ameen, Al Hussein Safaa Hussein, Ekhlas Khammas Hasan. The clinical applications of ferritin. World Journal of Biology Pharmacy and Health Sciences, 2022, 12(01), 137–147. Article DOI: https://doi.org/10.30574/wjbphs.2022.12.1.0143