Mechanical properties and biodegradability of crab shell-derived exoskeletons in orthopedic implant design

Joy Ene Idoko 1, *, Olubunmi Bashiru ­2, Toyosi Motilola Olola 3, Lawrence Anebi Enyejo 4 and Helena Nbéu Nkula Manuel 5

1 Department of Biomedical Engineering, University of Ibadan, Ibadan, Nigeria.
2 Department of Research and Development, The Energy Connoisseur L.L.C, Houston, Texas, USA.
3 Department of Communications, University of North Dakota, Grand Forks, USA.
4 Department of Telecommunications, Enforcement, Ancillary and Maintenance, National Broadcasting Commission Headquarters, Aso-Villa, Abuja, Nigeria.
5 Department of Architecture, College of Architecture Construction and Planning, The University of Texas at San Antonio, Texas, USA.
 
Review
World Journal of Biology Pharmacy and Health Sciences, 2024, 18(03), 116–131.
Article DOI: 10.30574/wjbphs.2024.18.3.0339
Publication history: 
Received on 29 April 2024; revised on 05 June 2024; accepted on 08 June 2024
 
Abstract: 
This review paper explores the innovative application of crab shell-derived exoskeleton materials, specifically chitin and chitosan, in the design of orthopedic implants. The urgent need for sustainable, biocompatible, and mechanically robust materials in medical applications guides this comprehensive analysis. We assess the mechanical properties of crab shell derivatives, highlighting their adequate strength and durability which are essential for successful orthopedic applications. This study also evaluates the biodegradability of these materials, an attribute that stands out for its potential to minimize long-term bodily impacts and reduce the need for secondary surgeries. Comparative analyses against traditional implant materials such as metals and ceramics are provided to underline the advantages and current limitations of crab shell-derived biopolymers. The review encompasses recent case studies and design innovations, including advanced fabrication techniques like 3D printing, which could integrate these biopolymers into future orthopedic solutions. Finally, we discuss the ongoing challenges and research gaps that must be addressed to harness the full potential of these biological materials in clinical settings. This paper aims to inform researchers and practitioners about the promising prospects of crab shell-derived materials, advocating for continued research and development in this promising area of orthopedic implant technology.
 
Keywords: 
Orthopedic Implants; Biodegradable; Crab Shell Exoskeletons; Mechanical Properties
 
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