Department of Pathology, Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.
World Journal of Biology Pharmacy and Health Sciences, 2026, 26(03), 302-312
Article DOI: 10.30574/wjbphs.2026.26.3.0363
Received on 14 May 2026; revised on 19 June 2026; accepted on 22 June 2026
Among many gynaecological malignancies ovarian cancer is the most prominent and leading cause of female mortality worldwide. The fifth edition of the World Health Organization of tumours of the female genital tract divided Ovarian tumours into four categories: Epithelial/Surface, Germ Cell, Sex Cord- Stromal and Metastasis on the basis of distinct risk factors, pathogenesis, pattern of spread, genetic profiles, response to chemotherapy, and outcomes. Molecular profiling has enabled to identify peculiar alterations occurring among histologic subtypes. Taken all data together, advancement of technology and enabling the exploration of novel biomarkers that may be able to provide more accurate diagnosis and improve prognosis of the patients.
Molecular profiling; Gynaecological malignacies; Ovarian tumours; Chemotherapy
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Rawat S, Arora N, Zaheer S and Ranga S. Recent updates in Ovarian Tumours: New recognized entities and molecular profiling according to the New 2020 WHO Classification of Female Genital Tumours. World Journal of Biology Pharmacy and Health Sciences, 2026, 26(03), 302-312. Article DOI: https://doi.org/10.30574/wjbphs.2026.26.3.0363