1 Department of Anaesthesiology, Panimalar College of Allied Health Sciences, Poonamallee, Chennai 600123, Tamil Nadu, India.
2 Department of Anaesthesiology, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
3 Department of Critical Care Medicine, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Kattankulathur – 603203, Tamil Nadu, India.
* Corresponding Author
ORCID Details
Getsyal Lionel: https://orcid.org/0009-0000-8413-5014
Anusha Jaganathan: https://orcid.org/0009-0009-8720-8018
Mohamed Azarudeen Musthak Ali: https://orcid.org/0009-0002-7193-5375
World Journal of Biology Pharmacy and Health Sciences, 2026, 27(03), 025–033
Article DOI: 10.30574/wjbphs.2026.27.3.0459
Received on 25 July 2026; revised on 05 September 2026; accepted on 07 September 2026
Background: Endotracheal tube (ETT) placement may provoke transient cardiovascular stimulation, whereas a laryngeal mask airway (LMA) avoids tracheal passage. Published comparisons remain procedure specific, and the magnitude of any immediate hemodynamic difference under routine anesthesia is uncertain.
Methods: This prospective, non-blinded two-group comparative study reanalysed complete individual-level data from 56 low-risk adults undergoing short elective surgery (LMA, n=26; ETT, n=30). Heart rate, systolic and diastolic blood pressure, and peripheral oxygen saturation were recorded before induction, after induction, immediately after airway placement, and at 3 and 5 minutes. The primary analytic contrast was the change from post-induction to immediate post-insertion. Change-score comparisons, participant fixed-effects trajectory models, and baseline-adjusted sensitivity models were used.
Results: The groups differed in sex distribution and in pre-induction heart rate and systolic blood pressure. From post-induction to immediate post-insertion, the LMA−ETT difference in change was −0.88 beats/min for heart rate (95% confidence interval [CI], −2.81 to 1.06; P=0.366), 2.98 mmHg for systolic blood pressure (95% CI, 0.31 to 5.65; P=0.030), and 1.01 mmHg for diastolic blood pressure (95% CI, −1.31 to 3.33; P=0.385). The systolic finding reflected a greater decrease in the ETT group. Serial device-by-time interactions were not significant for heart rate (P=0.055), systolic blood pressure (P=0.115), diastolic blood pressure (P=0.694), or oxygen saturation (P=0.312). At 0 minutes, adjusted ETT−LMA differences were not significant for heart rate (2.13 beats/min; 95% CI, −0.19 to 4.44), systolic blood pressure (−1.04 mmHg; 95% CI, −4.70 to 2.61), or diastolic blood pressure (−0.53 mmHg; 95% CI, −2.86 to 1.80).
Conclusions: In this cohort, both devices-maintained oxygenation and no statistically significant adjusted immediate hemodynamic advantage of LMA over ETT was demonstrated. The results support a claim of superior peri-insertion hemodynamic stability with LMA in this setting.
Laryngeal Mask Airway; Endotracheal Intubation; Hemodynamics; General Anesthesia; Perioperative Monitoring
Get Your e Certificate of Publication using below link
Preview Article PDF
Getsyal Lionel, Anusha Jaganathan and Mohamed Azarudeen Musthak Ali. HEMODYNAMIC RESPONSES AFTER LARYNGEAL MASK AIRWAY OR ENDOTRACHEAL TUBE PLACEMENT IN SHORT ELECTIVE SURGERY: A PROSPECTIVE COMPARATIVE STUDY. World Journal of Biology Pharmacy and Health Sciences, 2026, 27(03), 025–033. Article DOI: https://doi.org/10.30574/wjbphs.2026.27.3.0459