Antioxidant activity of leaves and bark extracts of Crataeva magna plant

Faheem I P 1, *, B. Gopalakrishna, Mohsina FP and Sarah Priya

1Acharya Nagarjuna University, Department of Pharmaceutical sciences, Guntur, India.
2Shridevi Institute of Pharmaceutical sciences, Tumkur, India.
3Luqman college of Pharmacy, Gulbarga. India.
4RME’S college of Pharmacy, Gulbarga, India.
 
Research Article
World Journal of Biology Pharmacy and Health Sciences, 2021, 05(01), 001-008.
Article DOI: 10.30574/wjbphs.2021.5.1.0106
Publication history: 
Received on 09 December 2020; revised on 16 December 2020; accepted on 18 December 2020
 
Abstract: 
Recently, a substantial body of literature provides strong evidence to support the potentials of Crataeva magna (CM), plant and its extracts in various pathological conditions. Thus, the CM plant extract at various concentrations were prepared and antioxidant activity was evaluated. The fresh leaves and bark of CM were collected and various extracts such as n-Hexane, Chloroform, Ethanol and aqueous extract were prepared. The preliminary phytochemical investigation showed the presence of various phytochemical such as total phenolic, flavonoid compounds and tannins. The ethanolic leaves extract of CM (ELECM) and water leaves extract of CM (WLECM), showed dose dependent increased in free radical scavenging activity in DPPH assay and reducing power assay in present study. Moreover, ethanolic barks extract of CM (EBECM) and water barks extract of CM (WBECM), also showed increased in free radical scavenging activity in DPPH assay and reducing power assay. However, the effects of bark extracts were lower than leaves extracts. In the light of the above consideration, the results of the study revealed that ELECM showed promising antioxidant activity in a dose dependent manner.
 
Keywords: 
Leaf Extract; Bark Extract; DPPH Assay; Reducing Power Assay; Antioxidant Activity
 
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