1 Assistant Professor, Department of Quality Assurance Technique, Samarth Institute of Pharmacy, Belhe, Pune, Maharashtra.
2 Student, Samarth Institute of Pharmacy, Belhe, Pune, Maharashtra.
World Journal of Biology Pharmacy and Health Sciences, 2025, 24(02), 054-058
Article DOI: 10.30574/wjbphs.2025.24.2.0940
Received on 21 September 2025; revised on 01 November 2025; accepted on 03 November 2025
Nitrofurantoin is a synthetic nitrofuran derivative widely used for the treatment and prevention of urinary tract infections (UTIs). It exhibits both bacteriostatic and bactericidal properties depending on its concentration. The formulation of Nitrofurantoin tablets aims to achieve optimum bioavailability, stability, and patient compliance. This review summarizes various approaches to the formulation and evaluation of Nitrofurantoin tablets, focusing on excipient selection, manufacturing methods, quality control parameters, and recent advances in sustained or controlled release systems.
Nitrofurantoin; Hydroxyl Propyl Methyl Cellulose (HPMC K4M; HPMC K100M); Xanthan Gum; Sustained Release
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Prachi Nandkumar Padwal, Akanksha Dattatray Khore, Reema Chandrakant Londhe, Madhavi Baban Aher, Mujeba Rajjak Pathan and Payal Hemant Padwal. Formulation, Development and evaluation of Nitrofurantoin tablets drug delivery systems. World Journal of Biology Pharmacy and Health Sciences, 2025, 24(02), 054-058. Article DOI: https://doi.org/10.30574/wjbphs.2025.24.2.0940.